Quinine
Not to be confused with quinidine, quinone, or quinoline. Quinine Clinical data Pronunciation US: / ˈ k w aɪ n aɪ n / , / k w ɪ ˈ n iː n / or UK: / ˈ k w ɪ n iː n / KWIN -een Trade names Qualaquin, Quinate, Quinbisul, others AHFS/Drugs.com Monograph MedlinePlus a682322 License data US FDA: Quinine Pregnancy category AU : D US : C (Risk not ruled out) Routes of administration By mouth, intramuscular, intravenous, rectal ATC code M09AA01 ( WHO ) P01BC01 ( WHO ) Legal status Legal status AU : S4 (Prescription only) CA : ℞-only UK : POM (Prescription only) US : ℞-only Pharmacokinetic data Protein binding 70–95% [1] Metabolism Liver (mostly CYP3A4 and CYP2C19-mediated) Elimination half-life 8–14 hours (adults), 6–12 hours (children) [1] Excretion Kidney (20%) Identifiers IUPAC name ( R )-(6-Methoxyquinolin-4-yl)[(1 S ,2 S ,4 S ,5 R )-5-vinylquinuclidin-2-yl]methanol CAS Nu...